Mitochondrial levels determine variability in cell death by modulating apoptotic gene expression

Fractional killing is the main cause of tumour resistance to chemotherapy. This phenomenon is observed even in genetically identical cancer cells in homogeneous microenvironments. To understand this variable resistance, here we investigate the individual responses to TRAIL in a clonal population of...

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Detalles Bibliográficos
Autores principales: Márquez-Jurado, Silvia, Díaz-Colunga, Juan, das Neves, Ricardo Pires, Martinez-Lorente, Antonio, Almazán, Fernando, Guantes, Raúl, Iborra, Francisco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785974/
https://www.ncbi.nlm.nih.gov/pubmed/29374163
http://dx.doi.org/10.1038/s41467-017-02787-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785974/
https://www.ncbi.nlm.nih.gov/pubmed/29374163
http://dx.doi.org/10.1038/s41467-017-02787-4

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