A dual role for the N-terminal domain of the IL-3 receptor in cell signalling

The interleukin-3 (IL-3) receptor is a cell-surface heterodimer that links the haemopoietic, vascular and immune systems and is overexpressed in acute and chronic myeloid leukaemia progenitor cells. It belongs to the type I cytokine receptor family in which the α-subunits consist of two fibronectin...

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Detalles Bibliográficos
Autores principales: Broughton, Sophie E., Hercus, Timothy R., Nero, Tracy L., Kan, Winnie L., Barry, Emma F., Dottore, Mara, Cheung Tung Shing, Karen S., Morton, Craig J., Dhagat, Urmi, Hardy, Matthew P., Wilson, Nicholas J., Downton, Matthew T., Schieber, Christine, Hughes, Timothy P., Lopez, Angel F., Parker, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785977/
https://www.ncbi.nlm.nih.gov/pubmed/29374162
http://dx.doi.org/10.1038/s41467-017-02633-7

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