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Long range haplotyping of paired-homologous chromosomes by single-chromosome sequencing of a single cell

The longest possible haplotype is chromosome haplotype that is a set of co-inherited alleles occurred on a single strand chromosome inherited from one parent. Standard whole-genome shotgun sequencing technologies are limited by the inability to independently study the haplotype of homologous chromos...

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Detalles Bibliográficos
Autores principales: Luo, Deng, Zhang, Meng, Liu, Ting, Cao, Wei, Guo, Jiajie, Mao, Caiping, Li, Yifan, Wang, Juanmei, Huang, Weiren, Lu, Daru, Zhang, Shuo, Li, Zhoufang, He, Jiankui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785984/
https://www.ncbi.nlm.nih.gov/pubmed/29374225
http://dx.doi.org/10.1038/s41598-018-20069-x

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