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Long range haplotyping of paired-homologous chromosomes by single-chromosome sequencing of a single cell
The longest possible haplotype is chromosome haplotype that is a set of co-inherited alleles occurred on a single strand chromosome inherited from one parent. Standard whole-genome shotgun sequencing technologies are limited by the inability to independently study the haplotype of homologous chromos...
Autores principales: | Luo, Deng, Zhang, Meng, Liu, Ting, Cao, Wei, Guo, Jiajie, Mao, Caiping, Li, Yifan, Wang, Juanmei, Huang, Weiren, Lu, Daru, Zhang, Shuo, Li, Zhoufang, He, Jiankui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785984/ https://www.ncbi.nlm.nih.gov/pubmed/29374225 http://dx.doi.org/10.1038/s41598-018-20069-x |
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