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Ceramide Synthase 6 Deficiency Enhances Inflammation in the DSS model of Colitis

Colitis, an inflammatory disease of the digestive tract, is increasing in incidence and prevalence. Intestinal inflammation can occur as a consequence of dysfunctions in sphingolipid metabolism. In this study we used ceramide synthase 6 (CerS6) deficient mice, which have a reduced ability to generat...

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Detalles Bibliográficos
Autores principales:	Helke, Kristi, Angel, Peggi, Lu, Ping, Garrett-Mayer, Elizabeth, Ogretmen, Besim, Drake, Richard, Voelkel-Johnson, Christina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786068/ https://www.ncbi.nlm.nih.gov/pubmed/29374263 http://dx.doi.org/10.1038/s41598-018-20102-z

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