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Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency
Recently, we reported that bacterial incorporation induces cellular transdifferentiation of human fibroblasts. However, the bacterium-intrinsic cellular- transdifferentiation factor remained unknown. Here, we found that cellular transdifferentiation is caused by ribosomes. Ribosomes, isolated from b...
Autores principales: | Ito, Naofumi, Katoh, Kaoru, Kushige, Hiroko, Saito, Yutaka, Umemoto, Terumasa, Matsuzaki, Yu, Kiyonari, Hiroshi, Kobayashi, Daiki, Soga, Minami, Era, Takumi, Araki, Norie, Furuta, Yasuhide, Suda, Toshio, Kida, Yasuyuki, Ohta, Kunimasa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786109/ https://www.ncbi.nlm.nih.gov/pubmed/29374279 http://dx.doi.org/10.1038/s41598-018-20057-1 |
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