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Disease-associated protein seeding suggests a dissociation between misfolded protein accumulation and neurodegeneration in prion disease
Chronic neurodegenerative diseases, such as prion diseases or Alzheimer's disease, are associated with progressive accumulation of host proteins which misfold and aggregate. Neurodegeneration is restricted to specific neuronal populations which show clear accumulation of misfolded proteins, whi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786362/ https://www.ncbi.nlm.nih.gov/pubmed/29023184 http://dx.doi.org/10.1080/19336896.2017.1378289 |