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Lupus miliaris disseminatus faciei
Lupus miliaris disseminatus faciei is a rare inflammatory dermatosis of unknown etiology that primarily affects young adults. Clinically, it is characterized by an asymptomatic papular eruption mainly involving the central face, typically on and around the eyelids. Characteristic histopathological f...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Dermatologia
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786405/ https://www.ncbi.nlm.nih.gov/pubmed/29364447 http://dx.doi.org/10.1590/abd1806-4841.20174534 |
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author | Toda-Brito, Helena Aranha, João Manuel Pires Tavares, Ermelindo Silva |
author_facet | Toda-Brito, Helena Aranha, João Manuel Pires Tavares, Ermelindo Silva |
author_sort | Toda-Brito, Helena |
collection | PubMed |
description | Lupus miliaris disseminatus faciei is a rare inflammatory dermatosis of unknown etiology that primarily affects young adults. Clinically, it is characterized by an asymptomatic papular eruption mainly involving the central face, typically on and around the eyelids. Characteristic histopathological features include dermal epithelioid cell granulomas with central necrosis and surrounding lymphocytic infiltrate with multinucleate giant cells. Lupus miliaris disseminatus faciei has a spontaneously resolving course, yet can be cosmetically debilitating given the location and potential for scarring. Treatment is difficult and there is a lack of controlled studies. We report a new case of lupus miliaris disseminatus faciei successfully treated with minocycline and systemic steroids, and briefly discuss its nosology and therapeutic options. |
format | Online Article Text |
id | pubmed-5786405 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Sociedade Brasileira de Dermatologia |
record_format | MEDLINE/PubMed |
spelling | pubmed-57864052018-02-01 Lupus miliaris disseminatus faciei Toda-Brito, Helena Aranha, João Manuel Pires Tavares, Ermelindo Silva An Bras Dermatol Case Report Lupus miliaris disseminatus faciei is a rare inflammatory dermatosis of unknown etiology that primarily affects young adults. Clinically, it is characterized by an asymptomatic papular eruption mainly involving the central face, typically on and around the eyelids. Characteristic histopathological features include dermal epithelioid cell granulomas with central necrosis and surrounding lymphocytic infiltrate with multinucleate giant cells. Lupus miliaris disseminatus faciei has a spontaneously resolving course, yet can be cosmetically debilitating given the location and potential for scarring. Treatment is difficult and there is a lack of controlled studies. We report a new case of lupus miliaris disseminatus faciei successfully treated with minocycline and systemic steroids, and briefly discuss its nosology and therapeutic options. Sociedade Brasileira de Dermatologia 2017 /pmc/articles/PMC5786405/ /pubmed/29364447 http://dx.doi.org/10.1590/abd1806-4841.20174534 Text en http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivative License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium provided the original work is properly cited and the work is not changed in any way. |
spellingShingle | Case Report Toda-Brito, Helena Aranha, João Manuel Pires Tavares, Ermelindo Silva Lupus miliaris disseminatus faciei |
title | Lupus miliaris disseminatus faciei |
title_full | Lupus miliaris disseminatus faciei |
title_fullStr | Lupus miliaris disseminatus faciei |
title_full_unstemmed | Lupus miliaris disseminatus faciei |
title_short | Lupus miliaris disseminatus faciei |
title_sort | lupus miliaris disseminatus faciei |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786405/ https://www.ncbi.nlm.nih.gov/pubmed/29364447 http://dx.doi.org/10.1590/abd1806-4841.20174534 |
work_keys_str_mv | AT todabritohelena lupusmiliarisdisseminatusfaciei AT aranhajoaomanuelpires lupusmiliarisdisseminatusfaciei AT tavaresermelindosilva lupusmiliarisdisseminatusfaciei |