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Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells
B cells constitute an essential line of defense from pathogenic infections through the generation of class-switched antibody-secreting cells (ASCs) in germinal centers. Although this process is known to be regulated by follicular helper T (TfH) cells, the mechanism by which B cells initially seed ge...
Autores principales: | Gaya, Mauro, Barral, Patricia, Burbage, Marianne, Aggarwal, Shweta, Montaner, Beatriz, Warren Navia, Andrew, Aid, Malika, Tsui, Carlson, Maldonado, Paula, Nair, Usha, Ghneim, Khader, Fallon, Padraic G., Sekaly, Rafick-Pierre, Barouch, Dan H., Shalek, Alex K., Bruckbauer, Andreas, Strid, Jessica, Batista, Facundo D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786505/ https://www.ncbi.nlm.nih.gov/pubmed/29249358 http://dx.doi.org/10.1016/j.cell.2017.11.036 |
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