Phenotyping of Mice with Heart Specific Overexpression of A(2A)-Adenosine Receptors: Evidence for Cardioprotective Effects of A(2A)-Adenosine Receptors

Background: Adenosine can be produced in the heart and acts on cardiac adenosine receptors. One of these receptors is the A(2A)-adenosine receptor (A(2A)-AR). Methods and Results: To better understand its role in cardiac function, we generated and characterized mice (A(2A)-TG) which overexpress the...

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Detalles Bibliográficos
Autores principales: Boknik, Peter, Drzewiecki, Katharina, Eskandar, John, Gergs, Ulrich, Grote-Wessels, Stephanie, Fabritz, Larissa, Kirchhof, Paulus, Müller, Frank U., Stümpel, Frank, Schmitz, Wilhelm, Zimmermann, Norbert, Kirchhefer, Uwe, Neumann, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786519/
https://www.ncbi.nlm.nih.gov/pubmed/29403384
http://dx.doi.org/10.3389/fphar.2018.00013

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