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‘Porcelain aorta’: a proposed definition and classification of ascending aortic calcification

INTRODUCTION: ‘Porcelain aorta’ is listed in the second consensus document of the Valve Academic Research Consortium as a risk factor in aortic valve replacement. However, the extent of circumferential involvement is poorly defined with great variability in reported incidence. We present a simple, r...

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Autores principales: Snow, Thomas, Semple, Thomas, Duncan, Alison, Barker, Sarah, Rubens, Michael, DiMario, Carlo, Davies, Simon, Moat, Neil, Nicol, Edward David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786940/
https://www.ncbi.nlm.nih.gov/pubmed/29387428
http://dx.doi.org/10.1136/openhrt-2017-000703
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author Snow, Thomas
Semple, Thomas
Duncan, Alison
Barker, Sarah
Rubens, Michael
DiMario, Carlo
Davies, Simon
Moat, Neil
Nicol, Edward David
author_facet Snow, Thomas
Semple, Thomas
Duncan, Alison
Barker, Sarah
Rubens, Michael
DiMario, Carlo
Davies, Simon
Moat, Neil
Nicol, Edward David
author_sort Snow, Thomas
collection PubMed
description INTRODUCTION: ‘Porcelain aorta’ is listed in the second consensus document of the Valve Academic Research Consortium as a risk factor in aortic valve replacement. However, the extent of circumferential involvement is poorly defined with great variability in reported incidence. We present a simple, reproducible classification to describe the extent of aortic calcification and thus appropriately define ‘porcelain aorta’, aiding clinical decision-making and registry data collection. METHODS: 175 consecutive CT aortograms were reviewed. The aorta was divided into three sections, and each section divided into quadrants. These were individually scored using a 5-point scale (0—no calcification, 5—complete contiguous calcification). Results for each quadrant were summated for each segment to provide an indication of the distribution of calcification. RESULTS: Only one patient (0.6%) had a ‘true’ porcelain aorta, defined as contiguous calcification across all quadrants at any aortic level. Intraobserver and interobserver variation was excellent for the ascending aorta (K=0.85–0.88 and 0.81–0.96, respectively) while the interobserver variation in the transverse arch was good at 0.75. CONCLUSIONS: Our data suggest the incidence of ‘true’ porcelain aorta may be significantly lower than reported in the literature. The predominance of calcification within the anterior wall of the proximal ascending aorta and the superior wall of the transverse arch may be clinically important. Application of this quick, simple and reproducible grading system, with no requirement for advanced software, may provide a tool to support accurate assessment of focal aortic calcification and its relationship to subsequent procedural risk.
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spelling pubmed-57869402018-01-31 ‘Porcelain aorta’: a proposed definition and classification of ascending aortic calcification Snow, Thomas Semple, Thomas Duncan, Alison Barker, Sarah Rubens, Michael DiMario, Carlo Davies, Simon Moat, Neil Nicol, Edward David Open Heart Aortic and Vascular Disease INTRODUCTION: ‘Porcelain aorta’ is listed in the second consensus document of the Valve Academic Research Consortium as a risk factor in aortic valve replacement. However, the extent of circumferential involvement is poorly defined with great variability in reported incidence. We present a simple, reproducible classification to describe the extent of aortic calcification and thus appropriately define ‘porcelain aorta’, aiding clinical decision-making and registry data collection. METHODS: 175 consecutive CT aortograms were reviewed. The aorta was divided into three sections, and each section divided into quadrants. These were individually scored using a 5-point scale (0—no calcification, 5—complete contiguous calcification). Results for each quadrant were summated for each segment to provide an indication of the distribution of calcification. RESULTS: Only one patient (0.6%) had a ‘true’ porcelain aorta, defined as contiguous calcification across all quadrants at any aortic level. Intraobserver and interobserver variation was excellent for the ascending aorta (K=0.85–0.88 and 0.81–0.96, respectively) while the interobserver variation in the transverse arch was good at 0.75. CONCLUSIONS: Our data suggest the incidence of ‘true’ porcelain aorta may be significantly lower than reported in the literature. The predominance of calcification within the anterior wall of the proximal ascending aorta and the superior wall of the transverse arch may be clinically important. Application of this quick, simple and reproducible grading system, with no requirement for advanced software, may provide a tool to support accurate assessment of focal aortic calcification and its relationship to subsequent procedural risk. BMJ Publishing Group 2018-01-26 /pmc/articles/PMC5786940/ /pubmed/29387428 http://dx.doi.org/10.1136/openhrt-2017-000703 Text en © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Aortic and Vascular Disease
Snow, Thomas
Semple, Thomas
Duncan, Alison
Barker, Sarah
Rubens, Michael
DiMario, Carlo
Davies, Simon
Moat, Neil
Nicol, Edward David
‘Porcelain aorta’: a proposed definition and classification of ascending aortic calcification
title ‘Porcelain aorta’: a proposed definition and classification of ascending aortic calcification
title_full ‘Porcelain aorta’: a proposed definition and classification of ascending aortic calcification
title_fullStr ‘Porcelain aorta’: a proposed definition and classification of ascending aortic calcification
title_full_unstemmed ‘Porcelain aorta’: a proposed definition and classification of ascending aortic calcification
title_short ‘Porcelain aorta’: a proposed definition and classification of ascending aortic calcification
title_sort ‘porcelain aorta’: a proposed definition and classification of ascending aortic calcification
topic Aortic and Vascular Disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786940/
https://www.ncbi.nlm.nih.gov/pubmed/29387428
http://dx.doi.org/10.1136/openhrt-2017-000703
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