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Significant transcriptional changes in 15q duplication but not Angelman syndrome deletion stem cell-derived neurons

BACKGROUND: The inability to analyze gene expression in living neurons from Angelman (AS) and Duplication 15q (Dup15q) syndrome subjects has limited our understanding of these disorders at the molecular level. METHOD: Here, we use dental pulp stem cells (DPSC) from AS deletion, 15q Duplication, and...

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Detalles Bibliográficos
Autores principales:	Urraca, Nora, Hope, Kevin, Victor, A. Kaitlyn, Belgard, T. Grant, Memon, Rawaha, Goorha, Sarita, Valdez, Colleen, Tran, Quynh T., Sanchez, Silvia, Ramirez, Juanma, Donaldson, Martin, Bridges, Dave, Reiter, Lawrence T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787244/ https://www.ncbi.nlm.nih.gov/pubmed/29423132 http://dx.doi.org/10.1186/s13229-018-0191-y

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