Cargando…
Secoisolariciresinol diglucoside is a blood-brain barrier protective and anti-inflammatory agent: implications for neuroinflammation
BACKGROUND: Secoisolariciresinol diglucoside (SDG), the main lignan in flaxseed, is known for its beneficial effects in inflammation, oxidative stress, heart disease, tumor progression, atherosclerosis, and diabetes. SDG might be an attractive natural compound that protects against neuroinflammation...
Autores principales: | Rom, Slava, Zuluaga-Ramirez, Viviana, Reichenbach, Nancy L., Erickson, Michelle A., Winfield, Malika, Gajghate, Sachin, Christofidou-Solomidou, Melpo, Jordan-Sciutto, Kelly L., Persidsky, Yuri |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787274/ https://www.ncbi.nlm.nih.gov/pubmed/29373982 http://dx.doi.org/10.1186/s12974-018-1065-0 |
Ejemplares similares
-
Synthetic Secoisolariciresinol Diglucoside Attenuates Established Pain, Oxidative Stress and Neuroinflammation in a Rodent Model of Painful Radiculopathy
por: Kartha, Sonia, et al.
Publicado: (2020) -
Combination of HIV-1 and Diabetes Enhances Blood Brain Barrier Injury via Effects on Brain Endothelium and Pericytes
por: Rom, Slava, et al.
Publicado: (2020) -
The Flaxseed-Derived Lignan Phenolic Secoisolariciresinol Diglucoside (SDG) Protects Non-Malignant Lung Cells from Radiation Damage
por: Velalopoulou, Anastasia, et al.
Publicado: (2015) -
The Synthetic Lignan Secoisolariciresinol Diglucoside Prevents Asbestos-Induced NLRP3 Inflammasome Activation in Murine Macrophages
por: Pietrofesa, Ralph A., et al.
Publicado: (2017) -
Synthetic Lignan Secoisolariciresinol Diglucoside (LGM2605) Reduces Asbestos-Induced Cytotoxicity in an Nrf2-Dependent and -Independent Manner
por: Pietrofesa, Ralph A., et al.
Publicado: (2018)