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c-Myb and C/EBPβ regulate OPN and other senescence-associated secretory phenotype factors

Tumorigenesis results from the convergence of cell autonomous mutations and corresponding stromal changes that promote tumor cell growth. Senescent cells, which secrete a plethora of pro-tumorigenic factors termed the senescence-associated secretory phenotype (SASP), play an important role in tumor...

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Detalles Bibliográficos
Autores principales: Flanagan, Kevin C., Alspach, Elise, Pazolli, Ermira, Parajuli, Shankar, Ren, Qihao, Arthur, Laura L., Tapia, Roberto, Stewart, Sheila A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787458/
https://www.ncbi.nlm.nih.gov/pubmed/29416593
http://dx.doi.org/10.18632/oncotarget.22940