Cargando…

HBXIP activates the PPARδ/NF-κB feedback loop resulting in cell proliferation

Hepatitis B X-interacting protein (HBXIP, also termed as LAMTOR5) plays a crucial role in regulation of cancer progression, while the mechanism is still unclear. Here we found that HBXIP increased the expression of PPARδ (peroxisome proliferator-activated receptor-δ) in gene and protein levels of SW...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Qian, Lu, Wenbin, Yang, Chunxia, Wang, Yue, Li, Wenjing, Chu, Ying, Deng, Jianzhong, Hou, Yongzhong, Jin, Jianhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787476/ https://www.ncbi.nlm.nih.gov/pubmed/29416623 http://dx.doi.org/10.18632/oncotarget.23057

Ejemplares similares

Inflammatory factor TNF-α promotes the growth of breast cancer via the positive feedback loop of TNFR1/NF-κB (and/or p38)/p-STAT3/HBXIP/TNFR1
por: Cai, Xiaoli, et al.
Publicado: (2017)

DPEP1 promotes drug resistance in colon cancer cells by forming a positive feedback loop with ASCL2
por: Zeng, Cheng, et al.
Publicado: (2022)

HBXIP induces anoikis resistance by forming a reciprocal feedback loop with Nrf2 to maintain redox homeostasis and stabilize Prdx1 in breast cancer
por: Zhou, Xiaolei, et al.
Publicado: (2022)

MiR‐145‐targeted HBXIP modulates human breast cancer cell proliferation
por: Jiang, Yang, et al.
Publicado: (2018)

AMPK phosphorylates PPARδ to mediate its stabilization, inhibit glucose and glutamine uptake and colon tumor growth
por: Ding, Jiajun, et al.
Publicado: (2021)

Peroxisome proliferator-activated receptors (PPARs) are potential drug targets for cancer therapy
por: Gou, Qian, et al.
Publicado: (2017)

lncRNA‐NKILA/NF‐κB feedback loop modulates laryngeal cancer cell proliferation, invasion, and radioresistance
por: Yang, Tao, et al.
Publicado: (2018)

Regulation of Cell Proliferation and Differentiation by PPARβ/δ
por: Müller, Rolf, et al.
Publicado: (2008)

COMMD7 is correlated with a novel NF-κB positive feedback loop in hepatocellular carcinoma
por: Zheng, Lu, et al.
Publicado: (2016)

HBXIP overexpression is correlated with the clinical features and survival outcome of ovarian cancer
por: Wang, Yixuan, et al.
Publicado: (2017)

NF-κB regulates neuronal ankyrin-G via a negative feedback loop
por: König, Hans-Georg, et al.
Publicado: (2017)

Nrf2, NF-κB and PPARβ/δ mRNA Expression Profile in Patients with Coronary Artery Disease
por: Barbosa, Jaqueline Ermida, et al.
Publicado: (2019)

Targeting Peroxisome Proliferator-Activated Receptor-β/δ (PPARβ/δ) for Cancer Chemoprevention
por: Peters, Jeffrey M., et al.
Publicado: (2015)

Germacrone Regulates HBXIP-Mediated Cell Cycle, Apoptosis and Promotes the Formation of Autophagosomes to Inhibit the Proliferation of Gastric Cancer Cells
por: Fang, Xing, et al.
Publicado: (2020)

HBXIP knockdown inhibits FHL2 to promote cycle arrest and suppress cervical cancer cell proliferation, invasion and migration
por: Gao, Xia, et al.
Publicado: (2023)

PPARδ regulates satellite cell proliferation and skeletal muscle regeneration
por: Angione, Alison R, et al.
Publicado: (2011)

NO-Donating NSAIDs, PPARδ, and Cancer: Does PPARδ Contribute to Colon Carcinogenesis?
por: Mackenzie, Gerardo G., et al.
Publicado: (2008)

The oncoprotein HBXIP activates transcriptional coregulatory protein LMO4 via Sp1 to promote proliferation of breast cancer cells
por: Yue, Lin, et al.
Publicado: (2013)

PPARα-Mediated Positive-Feedback Loop Contributes to Cold Exposure Memory
por: Alfaqaan, Soaad, et al.
Publicado: (2019)

The Role of NF-κB in PPARα-Mediated Hepatocarcinogenesis
por: Glauert, Howard P., et al.
Publicado: (2008)

PPAR-δ in Vascular Pathophysiology
por: Wang, Nanping
Publicado: (2008)

PPARα Enhances Cancer Cell Chemotherapy Sensitivity by Autophagy Induction
por: You, Mengli, et al.
Publicado: (2018)

Unraveling the role of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) expression in colon carcinogenesis
por: Peters, Jeffrey M., et al.
Publicado: (2019)

The Interaction of lncRNA-HEIH and lncRNA-HULC with HBXIP in Hepatitis B Patients
por: Ruan, Lingjuan, et al.
Publicado: (2018)

The oncoprotein HBXIP facilitates metastasis of hepatocellular carcinoma cells by activation of MMP15 expression
por: Zheng, Sen, et al.
Publicado: (2019)

Oncoprotein HBXIP promotes tumorigenesis through MAPK/ERK pathway activation in non-small cell lung cancer
por: Zhang, Jun, et al.
Publicado: (2021)

PPARγ and PPARδ as Modulators of Neoplasia and Cell Fate
por: Glazer, Robert I., et al.
Publicado: (2008)

Conditional Expression of Human PPARδ and a Dominant Negative Variant of hPPARδ In Vivo
por: Higgins, Larry G., et al.
Publicado: (2012)

USP15 inhibits multiple myeloma cell apoptosis through activating a feedback loop with the transcription factor NF-κBp65
por: Zhou, Lili, et al.
Publicado: (2018)

A novel positive feedback-loop between the HTLV-1 oncoprotein Tax and NF-κB activity in T-cells
por: Millen, Sebastian, et al.
Publicado: (2020)

Pin1 promotes pancreatic cancer progression and metastasis by activation of NF‐κB‐IL‐18 feedback loop
por: Sun, Qiqing, et al.
Publicado: (2020)

The negative feedback loop of NF-κB/miR-376b/NFKBIZ in septic acute kidney injury
por: Liu, Zhiwen, et al.
Publicado: (2020)

Unraveling the Role of Peroxisome Proliferator-Activated Receptor β/Δ (PPAR β/Δ) in Angiogenesis Associated with Multiple Myeloma
por: Leone, Patrizia, et al.
Publicado: (2023)

A positive feedback loop involving EGFR/Akt/mTORC1 and IKK/NF-κB regulates head and neck squamous cell carcinoma proliferation
por: Li, Zhipeng, et al.
Publicado: (2016)

Heme Oxygenase-1 Inhibits the Proliferation of Hepatic Stellate Cells by Activating PPARγ and Suppressing NF-κB
por: Yang, Hui, et al.
Publicado: (2022)

Peroxisome proliferator-activated receptors (PPARα, PPARγ and PPARβ/δ) gene expression profile on ram spermatozoa and their relation to the sperm motility
por: Kadivar, Ali, et al.
Publicado: (2016)

Oncogenic HBXIP enhances ZEB1 through Sp1 to accelerate breast cancer growth
por: Jiang, Yang, et al.
Publicado: (2018)

HBXIP blocks myosin-IIA assembly by phosphorylating and interacting with NMHC-IIA in breast cancer metastasis
por: Zhang, Lu, et al.
Publicado: (2023)

Naoxintong/PPARγ Signaling Inhibits Cardiac Hypertrophy via Activation of Autophagy
por: Yuan, Shuping, et al.
Publicado: (2017)

Investigating the Role of PPARβ/δ in Retinal Vascular Remodeling Using Pparβ/δ-Deficient Mice
por: Ho, Sze Yuan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_bbhnl3dv6ig7qrjqi1ar95suoi