Cargando…

In vitro and in vivo anti-leukemic effects of cladoloside C(2) are mediated by activation of Fas/ceramide synthase 6/p38 kinase/c-Jun NH(2)-terminal kinase/caspase-8

We previously demonstrated that the quinovose-containing hexaoside stichoposide C (STC) is a more potent anti-leukemic agent than the glucose-containing stichoposide D (STD), and that these substances have different molecular mechanisms of action. In the present study, we investigated the novel mari...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yun, Seong-Hoon, Sim, Eun-Hye, Han, Sang-Heum, Kim, Tae-Rang, Ju, Mi-Ha, Han, Jin-Yeong, Jeong, Jin-Sook, Kim, Sung-Hyun, Silchenko, Alexandra S., Stonik, Valentin A., Park, Joo-In
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787484/ https://www.ncbi.nlm.nih.gov/pubmed/29416631 http://dx.doi.org/10.18632/oncotarget.23069

Ejemplares similares

Matrix Survival Signaling: From Fibronectin via Focal Adhesion Kinase to C-Jun Nh(2)-Terminal Kinase
por: Almeida, Eduardo A.C., et al.
Publicado: (2000)

Regulation of c-Jun NH(2)-Terminal Kinase for Islet Transplantation
por: Noguchi, Hirofumi
Publicado: (2019)

Fist/Hipk3: A FAS/Fadd-Interacting Serine/Threonine Kinase That Induces Fadd Phosphorylation and Inhibits FAS-Mediated Jun Nh(2)-Terminal Kinase Activation
por: Rochat-Steiner, Véronique, et al.
Publicado: (2000)

By activating Fas/ceramide synthase 6/p38 kinase in lipid rafts, Stichoposide D inhibits growth of leukemia xenografts
por: Yun, Seong-Hoon, et al.
Publicado: (2015)

Inhibition of c-Jun NH(2)-terminal kinase or extracellular signal-regulated kinase improves lung injury
por: Lee, Hui Su, et al.
Publicado: (2004)

Regulation of FAS Ligand Expression during Activation-Induced Cell Death in T Cells by p38 Mitogen-Activated Protein Kinase and C-Jun Nh(2)-Terminal Kinase
por: Zhang, Jian, et al.
Publicado: (2000)

Activation of the c-Jun NH(2)-terminal kinase pathway by coronavirus infectious bronchitis virus promotes apoptosis independently of c-Jun
por: Fung, To Sing, et al.
Publicado: (2017)

Krox-20 inhibits Jun-NH(2)-terminal kinase/c-Jun to control Schwann cell proliferation and death
por: Parkinson, David B., et al.
Publicado: (2004)

c-Jun NH2-terminal kinase activation is essential for up-regulation of LC3 during ceramide-induced autophagy in human nasopharyngeal carcinoma cells
por: Sun, Ting, et al.
Publicado: (2011)

C-Jun NH(2)-Terminal Kinase Contributes to Dexmedetomidine-Induced Contraction in Isolated Rat Aortic Smooth Muscle
por: Ok, Seong-Ho, et al.
Publicado: (2011)

Arsenic Trioxide Induces Apoptosis in Human Platelets via C-Jun NH(2)-Terminal Kinase Activation
por: Wu, Yicun, et al.
Publicado: (2014)

The activation of c-Jun NH(2)-terminal kinase is required for dihydroartemisinin-induced autophagy in pancreatic cancer cells
por: Jia, Guang, et al.
Publicado: (2014)

ABL-N-induced apoptosis in human breast cancer cells is partially mediated by c-Jun NH(2)-terminal kinase activation
por: Liu, Bin, et al.
Publicado: (2010)

Regulation of c-Jun NH(2)-terminal Kinase ( Jnk) Gene Expression during T Cell Activation
por: Weiss, Linda, et al.
Publicado: (2000)

Specific effects of c-Jun NH2-terminal kinase-interacting protein 1 in neuronal axons
por: Tang, Shu, et al.
Publicado: (2016)

Role of the MAPK/cJun NH(2)-terminal kinase signaling pathway in starvation-induced autophagy
por: Barutcu, Seda Avcioglu, et al.
Publicado: (2018)

LYN kinase programs stromal fibroblasts to facilitate leukemic survival via regulation of c-JUN and THBS1
por: vom Stein, Alexander F., et al.
Publicado: (2023)

Poncirus trifoliata Rafin. induces the apoptosis of triple-negative breast cancer cells via activation of the c-Jun NH(2)-terminal kinase and extracellular signal-regulated kinase pathways
por: Han, Hye-Yeon, et al.
Publicado: (2015)

c-Jun NH2-terminal kinase suppression significantly inhibits the growth of transplanted breast tumors in mice
por: Huang, You-Cheng, et al.
Publicado: (2020)

NOD2/c-Jun NH(2)-Terminal Kinase Triggers Mycoplasma ovipneumoniae-Induced Macrophage Autophagy
por: Luo, Haixia, et al.
Publicado: (2020)

PKC-δ mediates interferon-α-induced apoptosis through c-Jun NH(2)-terminal kinase activation
por: Yanase, Noriko, et al.
Publicado: (2012)

G12 Signaling through c-Jun NH(2)-Terminal Kinase Promotes Breast Cancer Cell Invasion
por: Juneja, Juhi, et al.
Publicado: (2011)

The cJUN NH(2)-terminal kinase (JNK) signaling pathway promotes genome stability and prevents tumor initiation
por: Girnius, Nomeda, et al.
Publicado: (2018)

The cJUN NH(2)-terminal kinase (JNK) pathway contributes to mouse mammary gland remodeling during involution
por: Girnius, Nomeda, et al.
Publicado: (2018)

c-Jun N-Terminal Kinase Signaling Inhibitors Under Development
por: Han, Sun-Young
Publicado: (2008)

MAPK Kinase Kinase-1 Is Essential for Cytokine-Induced c-Jun NH(2)-Terminal Kinase and Nuclear Factor-κB Activation in Human Pancreatic Islet Cells
por: Mokhtari, Dariush, et al.
Publicado: (2008)

Excitatory transmission onto AgRP neurons is regulated by cJun NH(2)-terminal kinase 3 in response to metabolic stress
por: Vernia, Santiago, et al.
Publicado: (2016)

Mitogen-activated Protein Kinase Phosphatase-1 Represses c-Jun NH(2)-terminal Kinase-mediated Apoptosis via NF-κB Regulation
por: Wang, Zhaoqing, et al.
Publicado: (2008)

Coordinated transport of phosphorylated amyloid-β precursor protein and c-Jun NH(2)-terminal kinase–interacting protein-1
por: Muresan, Zoia, et al.
Publicado: (2005)

Increased phosphorylation of c-Jun NH (2)-terminal protein kinase in the sciatic nerves of Lewis rats with experimental autoimmune neuritis
por: Ahn, Meejung, et al.
Publicado: (2006)

c-Jun NH(2)-terminal kinase-dependent upregulation of DR5 mediates cooperative induction of apoptosis by perifosine and TRAIL
por: Fu, Lei, et al.
Publicado: (2010)

c-Jun NH(2)-Terminal Kinase 1/2 and Endoplasmic Reticulum Stress as Interdependent and Reciprocal Causation in Diabetic Embryopathy
por: Li, Xuezheng, et al.
Publicado: (2013)

Cloning and Functional Characterization of c-Jun NH(2)-Terminal Kinase from the Mediterranean Species of the Whitefly Bemisia tabaci Complex
por: Wang, Lan-Lan, et al.
Publicado: (2013)

c-Jun N-terminal kinase 2 suppresses pancreatic cancer growth and invasion and is opposed by c-Jun N-terminal kinase 1
por: Tian, Xiaodong, et al.
Publicado: (2021)

Anergic T cells are defective in both jun NH2-terminal kinase and mitogen-activated protein kinase signaling pathways
Publicado: (1996)

Serpin squamous cell carcinoma antigen inhibits UV-induced apoptosis via suppression of c-JUN NH(2)-terminal kinase
por: Katagiri, Chika, et al.
Publicado: (2006)

c-Jun NH(2)-Terminal Kinase (JNK)1 and JNK2 Have Distinct Roles in CD8(+) T Cell Activation
por: Conze, Dietrich, et al.
Publicado: (2002)

Anticancer activities of sulindac in prostate cancer cells associated with c-Jun NH2-terminal kinase 1/β-catenin signaling
por: DU, JUN, et al.
Publicado: (2014)

Pharmacological c-Jun NH(2)-Terminal Kinase (JNK) Pathway Inhibition Reduces Severity of Spinal Muscular Atrophy Disease in Mice
por: Schellino, Roberta, et al.
Publicado: (2018)

Involvement of Guanosine Triphosphatases and Phospholipase C-γ2 in Extracellular Signal–regulated Kinase, c-Jun NH(2)-terminal Kinase, and p38 Mitogen-activated Protein Kinase Activation by the B Cell Antigen Receptor
por: Hashimoto, Ari, et al.
Publicado: (1998)

Cannot write session to /tmp/vufind_sessions/sess_i3ud2t6jfg31dek5c2b4qti7o2