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Chemopreventative celecoxib fails to prevent schwannoma formation or sensorineural hearing loss in genetically engineered murine model of neurofibromatosis type 2

Mutations in the tumor suppressor gene NF2 lead to Neurofibromatosis type 2 (NF2), a tumor predisposition syndrome characterized by the development of schwannomas, including bilateral vestibular schwannomas with complete penetrance. Recent work has implicated the importance of COX-2 in schwannoma gr...

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Detalles Bibliográficos
Autores principales:	Wahle, Benjamin M., Hawley, Eric T., He, Yongzheng, Smith, Abbi E., Yuan, Jin, Masters, Andi R., Jones, David R., Gehlhausen, Jeffrey R., Park, Su-Jung, Conway, Simon J., Clapp, D. Wade, Yates, Charles W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787503/ https://www.ncbi.nlm.nih.gov/pubmed/29416648 http://dx.doi.org/10.18632/oncotarget.22002

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