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Gli is activated and promotes epithelial-mesenchymal transition in human esophageal adenocarcinoma

Esophageal adenocarcinoma (EAC) accounts for the most esophageal cancer cases in the US, and is notoriously aggressive. This study examines the role of Sonic Hedgehog (SHh)/Gli signaling in the regulation of epithelial-mesenchymal transition (EMT), a process tied to invasion and metastasis, in EAC....

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Detalles Bibliográficos
Autores principales: Wang, Lei, Jin, Joy Q., Zhou, Yong, Tian, Ziqiang, Jablons, David M., He, Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787518/
https://www.ncbi.nlm.nih.gov/pubmed/29416661
http://dx.doi.org/10.18632/oncotarget.22856