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Gli is activated and promotes epithelial-mesenchymal transition in human esophageal adenocarcinoma
Esophageal adenocarcinoma (EAC) accounts for the most esophageal cancer cases in the US, and is notoriously aggressive. This study examines the role of Sonic Hedgehog (SHh)/Gli signaling in the regulation of epithelial-mesenchymal transition (EMT), a process tied to invasion and metastasis, in EAC....
Autores principales: | Wang, Lei, Jin, Joy Q., Zhou, Yong, Tian, Ziqiang, Jablons, David M., He, Biao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787518/ https://www.ncbi.nlm.nih.gov/pubmed/29416661 http://dx.doi.org/10.18632/oncotarget.22856 |
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