Genomic landscape of colitis-associated cancer indicates the impact of chronic inflammation and its stratification by mutations in the Wnt signaling

Inflammatory bowel disease (IBD) increases the risk of colorectal cancer, known as colitis-associated cancer (CAC). It is still unclear what driver mutations are caused by chronic inflammation and lead to CAC development. To get insight into this issue, we investigated somatic alterations in CAC. We...

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Detalles Bibliográficos
Autores principales: Fujita, Masashi, Matsubara, Nagahide, Matsuda, Ikuo, Maejima, Kazuhiro, Oosawa, Ayako, Yamano, Tomoki, Fujimoto, Akihiro, Furuta, Mayuko, Nakano, Kaoru, Oku-Sasaki, Aya, Tanaka, Hiroko, Shiraishi, Yuichi, Mateos, Raúl Nicolás, Nakai, Kenta, Miyano, Satoru, Tomita, Naohiro, Hirota, Seiichi, Ikeuchi, Hiroki, Nakagawa, Hidewaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787528/
https://www.ncbi.nlm.nih.gov/pubmed/29416670
http://dx.doi.org/10.18632/oncotarget.22867

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