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Streptococcal Cysteine Protease-Mediated Cleavage of Desmogleins Is Involved in the Pathogenesis of Cutaneous Infection

Streptococcus pyogenes is responsible for a wide variety of cutaneous infections ranging from superficial impetigo to fulminant invasive necrotizing fasciitis. Dysfunction of desmosomes is associated with the pathogenesis of cutaneous diseases. We identified streptococcal pyrogenic exotoxin B (SpeB)...

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Detalles Bibliográficos
Autores principales: Sumitomo, Tomoko, Mori, Yasushi, Nakamura, Yuumi, Honda-Ogawa, Mariko, Nakagawa, Seitaro, Yamaguchi, Masaya, Matsue, Hiroyuki, Terao, Yutaka, Nakata, Masanobu, Kawabata, Shigetada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787553/
https://www.ncbi.nlm.nih.gov/pubmed/29416987
http://dx.doi.org/10.3389/fcimb.2018.00010