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Prior to Peripheral Tolerance, Newly Generated CD4 T Cells Maintain Dangerous Autoimmune Potential: Fas- and Perforin-Independent Autoimmunity Controlled by Programmed Death-1

Lymphopenia can result from various factors, including viral infections, clinical interventions, or as a normal property of the fetal/neonatal period. T cells in a lymphopenic environment undergo lymphopenia-induced proliferation (LIP) to fill the available “niche” as defined by peptide–MHC and home...

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Detalles Bibliográficos
Autores principales:	Ellestad, Kristofor K., Thangavelu, Govindarajan, Haile, Yohannes, Lin, Jiaxin, Boon, Louis, Anderson, Colin C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787554/ https://www.ncbi.nlm.nih.gov/pubmed/29416537 http://dx.doi.org/10.3389/fimmu.2018.00012

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