A Metadata Analysis of Oxidative Stress Etiology in Preclinical Amyotrophic Lateral Sclerosis: Benefits of Antioxidant Therapy

Oxidative stress, induced by an imbalance of free radicals, incites neurodegeneration in Amyotrophic Lateral Sclerosis (ALS). In fact, a mutation in antioxidant enzyme superoxide dismutase 1 (SOD1) accounts for 20% of familial ALS cases. However, the variance among individual studies examining ALS o...

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Detalles Bibliográficos
Autores principales: Bond, Leila, Bernhardt, Kamren, Madria, Priyank, Sorrentino, Katherine, Scelsi, Hailee, Mitchell, Cassie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787557/
https://www.ncbi.nlm.nih.gov/pubmed/29416499
http://dx.doi.org/10.3389/fnins.2018.00010

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