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Phenotypic dissection of the mouse Ren1d knockout by complementation with human renin

Normal renin synthesis and secretion is important for the maintenance of juxtaglomerular apparatus architecture. Mice lacking a functional Ren1d gene are devoid of renal juxtaglomerular cell granules and exhibit an altered macula densa morphology. Due to the species-specificity of renin activity, tr...

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Detalles Bibliográficos
Autores principales:	Buckley, Charlotte, Nelson, Robert J., Mullins, Linda J., Sharp, Matthew G. F., Fleming, Stewart, Kenyon, Christopher J., Semprini, Sabrina, Steppan, Dominik, Peti-Peterdi, Janos, Kurtz, Armin, Christian, Helen, Mullins, John J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2018
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787795/ https://www.ncbi.nlm.nih.gov/pubmed/29123029 http://dx.doi.org/10.1074/jbc.RA117.000160

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