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Inhibition of Cocaine and 3,4-Methylenedioxypyrovalerone (MDPV) Self-Administration by Lorcaserin Is Mediated by 5-HT2C Receptors in Rats

Lorcaserin is a serotonin (5-HT)(2C) receptor-preferring agonist approved by the US Food and Drug Administration to treat obesity. Lorcaserin decreases cocaine self-administration in rats and monkeys. Although this effect is partially inhibited by a 5-HT(2C) receptor antagonist (SB242084), lorcaseri...

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Detalles Bibliográficos
Autores principales:	Gannon, Brenda M., Sulima, Agnieszka, Rice, Kenner C., Collins, Gregory T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Pharmacology and Experimental Therapeutics 2018
Materias:	Behavioral Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787931/ https://www.ncbi.nlm.nih.gov/pubmed/29217539 http://dx.doi.org/10.1124/jpet.117.246082

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