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Paraquat poisoning: Case report of a survivor
N, N′-dimethyl-4, 4′-bipyridinium dichloride (paraquat) is a widely used synthetic, nonselective contact herbicide. Ingestion of toxic doses of paraquat can be fatal with life-threatening effects on the lungs, gastrointestinal (GI) tract, kidney, liver, heart, and other organs. Till date, there are...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787979/ https://www.ncbi.nlm.nih.gov/pubmed/29417032 http://dx.doi.org/10.4103/2249-4863.222042 |
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author | Janeela, M. Asisha Oommen, Ajoy Misra, Ajay Kumar Ramya, I. |
author_facet | Janeela, M. Asisha Oommen, Ajoy Misra, Ajay Kumar Ramya, I. |
author_sort | Janeela, M. Asisha |
collection | PubMed |
description | N, N′-dimethyl-4, 4′-bipyridinium dichloride (paraquat) is a widely used synthetic, nonselective contact herbicide. Ingestion of toxic doses of paraquat can be fatal with life-threatening effects on the lungs, gastrointestinal (GI) tract, kidney, liver, heart, and other organs. Till date, there are no specific antidotes and none of the current treatments have proven efficacious. The prognosis is uniformly poor worldwide, including those who treat aggressively with multimodal therapies. Long-term survivors are few, and have GI and pulmonary complications. Hence, prevention needs to be the utmost priority, and on exposure, aggressive decontamination should be initiated. Although it is a very common herbicide, there are very few cases reported from India and awareness among people needs to be widened. |
format | Online Article Text |
id | pubmed-5787979 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-57879792018-02-07 Paraquat poisoning: Case report of a survivor Janeela, M. Asisha Oommen, Ajoy Misra, Ajay Kumar Ramya, I. J Family Med Prim Care Case Report N, N′-dimethyl-4, 4′-bipyridinium dichloride (paraquat) is a widely used synthetic, nonselective contact herbicide. Ingestion of toxic doses of paraquat can be fatal with life-threatening effects on the lungs, gastrointestinal (GI) tract, kidney, liver, heart, and other organs. Till date, there are no specific antidotes and none of the current treatments have proven efficacious. The prognosis is uniformly poor worldwide, including those who treat aggressively with multimodal therapies. Long-term survivors are few, and have GI and pulmonary complications. Hence, prevention needs to be the utmost priority, and on exposure, aggressive decontamination should be initiated. Although it is a very common herbicide, there are very few cases reported from India and awareness among people needs to be widened. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5787979/ /pubmed/29417032 http://dx.doi.org/10.4103/2249-4863.222042 Text en Copyright: © 2017 Journal of Family Medicine and Primary Care http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Janeela, M. Asisha Oommen, Ajoy Misra, Ajay Kumar Ramya, I. Paraquat poisoning: Case report of a survivor |
title | Paraquat poisoning: Case report of a survivor |
title_full | Paraquat poisoning: Case report of a survivor |
title_fullStr | Paraquat poisoning: Case report of a survivor |
title_full_unstemmed | Paraquat poisoning: Case report of a survivor |
title_short | Paraquat poisoning: Case report of a survivor |
title_sort | paraquat poisoning: case report of a survivor |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787979/ https://www.ncbi.nlm.nih.gov/pubmed/29417032 http://dx.doi.org/10.4103/2249-4863.222042 |
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