Cargando…

Paraquat poisoning: Case report of a survivor

N, N′-dimethyl-4, 4′-bipyridinium dichloride (paraquat) is a widely used synthetic, nonselective contact herbicide. Ingestion of toxic doses of paraquat can be fatal with life-threatening effects on the lungs, gastrointestinal (GI) tract, kidney, liver, heart, and other organs. Till date, there are...

Descripción completa

Detalles Bibliográficos
Autores principales: Janeela, M. Asisha, Oommen, Ajoy, Misra, Ajay Kumar, Ramya, I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787979/
https://www.ncbi.nlm.nih.gov/pubmed/29417032
http://dx.doi.org/10.4103/2249-4863.222042
_version_ 1783296034658582528
author Janeela, M. Asisha
Oommen, Ajoy
Misra, Ajay Kumar
Ramya, I.
author_facet Janeela, M. Asisha
Oommen, Ajoy
Misra, Ajay Kumar
Ramya, I.
author_sort Janeela, M. Asisha
collection PubMed
description N, N′-dimethyl-4, 4′-bipyridinium dichloride (paraquat) is a widely used synthetic, nonselective contact herbicide. Ingestion of toxic doses of paraquat can be fatal with life-threatening effects on the lungs, gastrointestinal (GI) tract, kidney, liver, heart, and other organs. Till date, there are no specific antidotes and none of the current treatments have proven efficacious. The prognosis is uniformly poor worldwide, including those who treat aggressively with multimodal therapies. Long-term survivors are few, and have GI and pulmonary complications. Hence, prevention needs to be the utmost priority, and on exposure, aggressive decontamination should be initiated. Although it is a very common herbicide, there are very few cases reported from India and awareness among people needs to be widened.
format Online
Article
Text
id pubmed-5787979
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-57879792018-02-07 Paraquat poisoning: Case report of a survivor Janeela, M. Asisha Oommen, Ajoy Misra, Ajay Kumar Ramya, I. J Family Med Prim Care Case Report N, N′-dimethyl-4, 4′-bipyridinium dichloride (paraquat) is a widely used synthetic, nonselective contact herbicide. Ingestion of toxic doses of paraquat can be fatal with life-threatening effects on the lungs, gastrointestinal (GI) tract, kidney, liver, heart, and other organs. Till date, there are no specific antidotes and none of the current treatments have proven efficacious. The prognosis is uniformly poor worldwide, including those who treat aggressively with multimodal therapies. Long-term survivors are few, and have GI and pulmonary complications. Hence, prevention needs to be the utmost priority, and on exposure, aggressive decontamination should be initiated. Although it is a very common herbicide, there are very few cases reported from India and awareness among people needs to be widened. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5787979/ /pubmed/29417032 http://dx.doi.org/10.4103/2249-4863.222042 Text en Copyright: © 2017 Journal of Family Medicine and Primary Care http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Janeela, M. Asisha
Oommen, Ajoy
Misra, Ajay Kumar
Ramya, I.
Paraquat poisoning: Case report of a survivor
title Paraquat poisoning: Case report of a survivor
title_full Paraquat poisoning: Case report of a survivor
title_fullStr Paraquat poisoning: Case report of a survivor
title_full_unstemmed Paraquat poisoning: Case report of a survivor
title_short Paraquat poisoning: Case report of a survivor
title_sort paraquat poisoning: case report of a survivor
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787979/
https://www.ncbi.nlm.nih.gov/pubmed/29417032
http://dx.doi.org/10.4103/2249-4863.222042
work_keys_str_mv AT janeelamasisha paraquatpoisoningcasereportofasurvivor
AT oommenajoy paraquatpoisoningcasereportofasurvivor
AT misraajaykumar paraquatpoisoningcasereportofasurvivor
AT ramyai paraquatpoisoningcasereportofasurvivor