Mutual Regulation of Tumour Vessel Normalization and Immunostimulatory Reprogramming

Blockade of angiogenesis can retard tumour growth, but may also paradoxically increase metastasis(1,2). Vessel normalization (VN) may resolve this paradox(3). VN involves increased pericyte coverage, improved tumour vessel perfusion, reduced vascular permeability, and consequently mitigated hypoxia(...

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Detalles Bibliográficos
Autores principales: Tian, Lin, Goldstein, Amit, Wang, Hai, Lo, Hin Ching, Kim, Ik Sun, Welte, Thomas, Sheng, Kuanwei, Dobrolecki, Lacey E., Zhang, Xiaomei, Putluri, Nagireddy, Phung, Thuy L., Mani, Sendurai A., Stossi, Fabio, Sreekumar, Arun, Mancini, Michael A., Decker, William K., Zong, Chenghang, Lewis, Michael T., Zhang, Xiang H.-F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788037/
https://www.ncbi.nlm.nih.gov/pubmed/28371798
http://dx.doi.org/10.1038/nature21724

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