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Chromosome choice for initiation of V-(D)-J recombination is not governed by genomic imprinting

V-(D)-J recombination generates the antigen receptor diversity necessary for immune cell function while allelic exclusion ensures that each cell expresses a single antigen-receptor. V-(D)-J recombination of the Ig, Tcrb, Tcrg, and Tcrd antigen receptor genes is ordered and sequential so that only on...

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Detalles Bibliográficos
Autores principales:	Gebert, Claudia, Correia, Lauren, Li, Zhenhu, Petrie, Howard T, Love, Paul E, Pfeifer, Karl
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788196/ https://www.ncbi.nlm.nih.gov/pubmed/28244489 http://dx.doi.org/10.1038/icb.2017.1

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