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The ER membrane protein complex is a transmembrane domain insertase

Insertion of proteins into membranes is an essential cellular process. The extensive biophysical and topological diversity of membrane proteins necessitates multiple insertion pathways that remain incompletely defined. Here we found that known membrane insertion pathways fail to effectively engage t...

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Detalles Bibliográficos
Autores principales:	Guna, Alina, Volkmar, Norbert, Christianson, John C., Hegde, Ramanujan S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2017
Materias:	Membrane Targeting
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788257/ https://www.ncbi.nlm.nih.gov/pubmed/29242231 http://dx.doi.org/10.1126/science.aao3099

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