Substrate Sorting by a Supercharged Nanoreactor

[Image: see text] Compartmentalization of proteases enables spatially and temporally controlled protein degradation in cells. Here we show that an engineered lumazine synthase protein cage, which possesses a negatively supercharged lumen, can exploit electrostatic effects to sort substrates for an e...

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Detalles Bibliográficos
Autores principales: Azuma, Yusuke, Bader, Daniel L. V., Hilvert, Donald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788330/
https://www.ncbi.nlm.nih.gov/pubmed/29278496
http://dx.doi.org/10.1021/jacs.7b11210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788330/
https://www.ncbi.nlm.nih.gov/pubmed/29278496
http://dx.doi.org/10.1021/jacs.7b11210

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