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Substrate Sorting by a Supercharged Nanoreactor
[Image: see text] Compartmentalization of proteases enables spatially and temporally controlled protein degradation in cells. Here we show that an engineered lumazine synthase protein cage, which possesses a negatively supercharged lumen, can exploit electrostatic effects to sort substrates for an e...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788330/ https://www.ncbi.nlm.nih.gov/pubmed/29278496 http://dx.doi.org/10.1021/jacs.7b11210 |