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The development of a stochastic mathematical model of Alzheimer’s disease to help improve the design of clinical trials of potential treatments
Alzheimer’s disease (AD) is a neurodegenerative disorder characterised by a slow progressive deterioration of cognitive capacity. Drugs are urgently needed for the treatment of AD and unfortunately almost all clinical trials of AD drug candidates have failed or been discontinued to date. Mathematica...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788351/ https://www.ncbi.nlm.nih.gov/pubmed/29377891 http://dx.doi.org/10.1371/journal.pone.0190615 |