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Vitamin A status in healthy women eating traditionally prepared spirulina (Dihé) in the Chad Lake area
BACKGROUND: Chad Lake is a central place in a region with a high prevalence of vitamin A deficiency. Spirulina, a natural source of β-carotene, is traditionally produced and eaten as “Dihé” around Chad Lake. β-carotene spirulina has been found to have a high conversion factor to retinol. The aim of...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788361/ https://www.ncbi.nlm.nih.gov/pubmed/29377934 http://dx.doi.org/10.1371/journal.pone.0191887 |
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author | Soudy, Imar Djibrine Minet-Quinard, Régine Mahamat, Alhadj Djidda Ngoua, Hadjé Fatimé Izzedine, Abdelaziz Arada Tidjani, Abdelsalam Ngo Bum, Elisabeth Lambert, Céline Pereira, Bruno Desjeux, Jehan-François Sapin, Vincent |
author_facet | Soudy, Imar Djibrine Minet-Quinard, Régine Mahamat, Alhadj Djidda Ngoua, Hadjé Fatimé Izzedine, Abdelaziz Arada Tidjani, Abdelsalam Ngo Bum, Elisabeth Lambert, Céline Pereira, Bruno Desjeux, Jehan-François Sapin, Vincent |
author_sort | Soudy, Imar Djibrine |
collection | PubMed |
description | BACKGROUND: Chad Lake is a central place in a region with a high prevalence of vitamin A deficiency. Spirulina, a natural source of β-carotene, is traditionally produced and eaten as “Dihé” around Chad Lake. β-carotene spirulina has been found to have a high conversion factor to retinol. The aim of the study was to assess if the retinol status between healthy women eating spirulina Dihé daily (SPI+) and not (SPI-) in the Chad Lake area was different. METHODS: This study was observational: 88 healthy women were recruited and selected according to clinical criteria and their willingness to participate. They were divided in two groups according to their Dihé daily consumption: those who eat Dihé (SPI+; n = 35) and those who do not (SPI-; n = 35). After anthropometric and dietary assessments, blood retinol, β-carotene, retinol binding, and inflammatory/nutritional proteins were measured. RESULTS: The diet between groups was identical, except for β-carotene consumption, which was higher in SPI+ than in SPI- (10.8 vs. 1.8 mg/day). The serum retinol and β-carotene concentrations were significantly higher in SPI+ than in SPI- at 1.26 ± 0.36 μmol/l versus 1.03 ± 0.31 μmol/l (p = 0.008) and 0.59 ±0.37 μmol/l versus 0.46± 0.31 μmol/l (p = 0.04), respectively. Seventy-seven percent of SPI+ versus 29% of SPI- had an adequate blood retinol value (p = 0.01). CONCLUSION: The results confirm that β-carotene in spirulina is an effective positive modulator of blood retinol status. Dihé is a potential natural source of β-carotene to achieve a proper vitamin A status in healthy women living near Chad Lake. |
format | Online Article Text |
id | pubmed-5788361 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-57883612018-02-09 Vitamin A status in healthy women eating traditionally prepared spirulina (Dihé) in the Chad Lake area Soudy, Imar Djibrine Minet-Quinard, Régine Mahamat, Alhadj Djidda Ngoua, Hadjé Fatimé Izzedine, Abdelaziz Arada Tidjani, Abdelsalam Ngo Bum, Elisabeth Lambert, Céline Pereira, Bruno Desjeux, Jehan-François Sapin, Vincent PLoS One Research Article BACKGROUND: Chad Lake is a central place in a region with a high prevalence of vitamin A deficiency. Spirulina, a natural source of β-carotene, is traditionally produced and eaten as “Dihé” around Chad Lake. β-carotene spirulina has been found to have a high conversion factor to retinol. The aim of the study was to assess if the retinol status between healthy women eating spirulina Dihé daily (SPI+) and not (SPI-) in the Chad Lake area was different. METHODS: This study was observational: 88 healthy women were recruited and selected according to clinical criteria and their willingness to participate. They were divided in two groups according to their Dihé daily consumption: those who eat Dihé (SPI+; n = 35) and those who do not (SPI-; n = 35). After anthropometric and dietary assessments, blood retinol, β-carotene, retinol binding, and inflammatory/nutritional proteins were measured. RESULTS: The diet between groups was identical, except for β-carotene consumption, which was higher in SPI+ than in SPI- (10.8 vs. 1.8 mg/day). The serum retinol and β-carotene concentrations were significantly higher in SPI+ than in SPI- at 1.26 ± 0.36 μmol/l versus 1.03 ± 0.31 μmol/l (p = 0.008) and 0.59 ±0.37 μmol/l versus 0.46± 0.31 μmol/l (p = 0.04), respectively. Seventy-seven percent of SPI+ versus 29% of SPI- had an adequate blood retinol value (p = 0.01). CONCLUSION: The results confirm that β-carotene in spirulina is an effective positive modulator of blood retinol status. Dihé is a potential natural source of β-carotene to achieve a proper vitamin A status in healthy women living near Chad Lake. Public Library of Science 2018-01-29 /pmc/articles/PMC5788361/ /pubmed/29377934 http://dx.doi.org/10.1371/journal.pone.0191887 Text en © 2018 Soudy et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Soudy, Imar Djibrine Minet-Quinard, Régine Mahamat, Alhadj Djidda Ngoua, Hadjé Fatimé Izzedine, Abdelaziz Arada Tidjani, Abdelsalam Ngo Bum, Elisabeth Lambert, Céline Pereira, Bruno Desjeux, Jehan-François Sapin, Vincent Vitamin A status in healthy women eating traditionally prepared spirulina (Dihé) in the Chad Lake area |
title | Vitamin A status in healthy women eating traditionally prepared spirulina (Dihé) in the Chad Lake area |
title_full | Vitamin A status in healthy women eating traditionally prepared spirulina (Dihé) in the Chad Lake area |
title_fullStr | Vitamin A status in healthy women eating traditionally prepared spirulina (Dihé) in the Chad Lake area |
title_full_unstemmed | Vitamin A status in healthy women eating traditionally prepared spirulina (Dihé) in the Chad Lake area |
title_short | Vitamin A status in healthy women eating traditionally prepared spirulina (Dihé) in the Chad Lake area |
title_sort | vitamin a status in healthy women eating traditionally prepared spirulina (dihé) in the chad lake area |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788361/ https://www.ncbi.nlm.nih.gov/pubmed/29377934 http://dx.doi.org/10.1371/journal.pone.0191887 |
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