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Identification of cell cycle-targeting microRNAs through genome-wide screens

By performing nine genome-wide microRNA (miRNA) screens, we recently uncovered a new class of miRNAs, which target multiple cyclins and cyclin-dependent kinases (CDKs). Systemic delivery of selected cell cycle-targeting miRNAs to mouse xenograft models resulted in potent anti-tumorigenic effects wit...

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Detalles Bibliográficos
Autores principales:	Hydbring, Per, Wang, Yinan, Bogorad, Roman L., Yin, Hao, Anderson, Daniel G., Li, Cheng, Sicinski, Piotr
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2017
Materias:	Extra View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788471/ https://www.ncbi.nlm.nih.gov/pubmed/29099267 http://dx.doi.org/10.1080/15384101.2017.1380132

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