Cargando…

Portraits of a pressure sensor

Near atomic-resolution structures have provided insights into the mechanisms by which the Piezo1 ion channel senses and responds to mechanical stimuli.

Detalles Bibliográficos
Autores principales:	Chesler, Alexander T, Szczot, Marcin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2018
Materias:	Biophysics and Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788499/ https://www.ncbi.nlm.nih.gov/pubmed/29376828 http://dx.doi.org/10.7554/eLife.34396

Ejemplares similares

Phosphatidic acid modulation of Kv channel voltage sensor function
por: Hite, Richard K, et al.
Publicado: (2014)

Proton currents constrain structural models of voltage sensor activation
por: Randolph, Aaron L, et al.
Publicado: (2016)

Single-fluorophore membrane transport activity sensors with dual-emission read-out
por: Ast, Cindy, et al.
Publicado: (2015)

The innate immune sensor IFI16 recognizes foreign DNA in the nucleus by scanning along the duplex
por: Stratmann, Sarah A, et al.
Publicado: (2015)

STIMulating blood pressure
por: Garrud, Tessa AC, et al.
Publicado: (2022)

Increasing evidence of mechanical force as a functional regulator in smooth muscle myosin light chain kinase
por: Baumann, Fabian, et al.
Publicado: (2017)

A mutation uncouples the tubulin conformational and GTPase cycles, revealing allosteric control of microtubule dynamics
por: Geyer, Elisabeth A, et al.
Publicado: (2015)

Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms
por: Kober, Daniel L, et al.
Publicado: (2016)

Single-molecule imaging of telomerase reverse transcriptase in human telomerase holoenzyme and minimal RNP complexes
por: Wu, Robert Alexander, et al.
Publicado: (2015)

Biophysical basis for convergent evolution of two veil-forming microbes
por: Petroff, Alexander P., et al.
Publicado: (2015)

Structural dynamics of E. coli single-stranded DNA binding protein reveal DNA wrapping and unwrapping pathways
por: Suksombat, Sukrit, et al.
Publicado: (2015)

Direct single molecule measurement of TCR triggering by agonist pMHC in living primary T cells
por: O'Donoghue, Geoff P, et al.
Publicado: (2013)

CryoEM structures of membrane pore and prepore complex reveal cytolytic mechanism of Pneumolysin
por: van Pee, Katharina, et al.
Publicado: (2017)

Scaffold nucleoporins Nup188 and Nup192 share structural and functional properties with nuclear transport receptors
por: Andersen, Kasper R, et al.
Publicado: (2013)

Correction: Additive effects on the energy barrier for synaptic vesicle fusion cause supralinear effects on the vesicle fusion rate
por: Schotten, Sebastiaan, et al.
Publicado: (2015)

Additive effects on the energy barrier for synaptic vesicle fusion cause supralinear effects on the vesicle fusion rate
por: Schotten, Sebastiaan, et al.
Publicado: (2015)

MutS/MutL crystal structure reveals that the MutS sliding clamp loads MutL onto DNA
por: Groothuizen, Flora S, et al.
Publicado: (2015)

Huntingtin’s spherical solenoid structure enables polyglutamine tract-dependent modulation of its structure and function
por: Vijayvargia, Ravi, et al.
Publicado: (2016)

TMEM266 is a functional voltage sensor regulated by extracellular Zn(2+)
por: Papp, Ferenc, et al.
Publicado: (2019)

Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network
por: Nwachukwu, Jerome C, et al.
Publicado: (2014)

Conformational dynamics of auto-inhibition in the ER calcium sensor STIM1
por: van Dorp, Stijn, et al.
Publicado: (2021)

Identification of a pre-active conformation of a pentameric channel receptor
por: Menny, Anaïs, et al.
Publicado: (2017)

Model for a novel membrane envelope in a filamentous hyperthermophilic virus
por: Kasson, Peter, et al.
Publicado: (2017)

A pH-driven transition of the cytoplasm from a fluid- to a solid-like state promotes entry into dormancy
por: Munder, Matthias Christoph, et al.
Publicado: (2016)

A surprising twist
por: Fakhri, Nikta, et al.
Publicado: (2014)

Trainspotting in a cilium
por: Kumar, Dhivya, et al.
Publicado: (2017)

A tethered delivery mechanism explains the catalytic action of a microtubule polymerase
por: Ayaz, Pelin, et al.
Publicado: (2014)

A structural mechanism for bacterial autotransporter glycosylation by a dodecameric heptosyltransferase family
por: Yao, Qing, et al.
Publicado: (2014)

Serum amyloid A is a retinol binding protein that transports retinol during bacterial infection
por: Derebe, Mehabaw G, et al.
Publicado: (2014)

Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel
por: Banerjee, Anirban, et al.
Publicado: (2013)

Structure of a Holliday junction complex reveals mechanisms governing a highly regulated DNA transaction
por: Laxmikanthan, Gurunathan, et al.
Publicado: (2016)

How to switch a master switch
por: Hein, Christopher, et al.
Publicado: (2013)

Finding FISH in a small pond
por: Jan, Calvin H
Publicado: (2016)

An intimate view of a spliceosome component
por: Nilsen, Timothy W
Publicado: (2015)

Folding behavior of a T-shaped, ribosome-binding translation enhancer implicated in a wide-spread conformational switch
por: Le, My-Tra, et al.
Publicado: (2017)

Crystal structure and dynamics of a lipid-induced potential desensitized-state of a pentameric ligand-gated channel
por: Basak, Sandip, et al.
Publicado: (2017)

Building a super elongation complex for HIV
por: Hill, Christopher P, et al.
Publicado: (2013)

Cryo-EM enters a new era
por: Kühlbrandt, Werner
Publicado: (2014)

Mechanical design principles of a mitotic spindle
por: Ward, Jonathan J, et al.
Publicado: (2014)

Convergent weaponry in a biological arms race
por: Baker, Edward N, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_1ru7qtohhc9brdcl6u5iejmjsj