Hsp70-associated chaperones have a critical role in buffering protein production costs

Proteins are necessary for cellular growth. Concurrently, however, protein production has high energetic demands associated with transcription and translation. Here, we propose that activity of molecular chaperones shape protein burden, that is the fitness costs associated with expression of unneede...

Descripción completa

Detalles Bibliográficos
Autores principales: Farkas, Zoltán, Kalapis, Dorottya, Bódi, Zoltán, Szamecz, Béla, Daraba, Andreea, Almási, Karola, Kovács, Károly, Boross, Gábor, Pál, Ferenc, Horváth, Péter, Balassa, Tamás, Molnár, Csaba, Pettkó-Szandtner, Aladár, Klement, Éva, Rutkai, Edit, Szvetnik, Attila, Papp, Balázs, Pál, Csaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788500/
https://www.ncbi.nlm.nih.gov/pubmed/29377792
http://dx.doi.org/10.7554/eLife.29845

Ejemplares similares

Ejemplares similares