Prediction of enzymatic pathways by integrative pathway mapping

The functions of most proteins are yet to be determined. The function of an enzyme is often defined by its interacting partners, including its substrate and product, and its role in larger metabolic networks. Here, we describe a computational method that predicts the functions of orphan enzymes by o...

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Detalles Bibliográficos
Autores principales: Calhoun, Sara, Korczynska, Magdalena, Wichelecki, Daniel J, San Francisco, Brian, Zhao, Suwen, Rodionov, Dmitry A, Vetting, Matthew W, Al-Obaidi, Nawar F, Lin, Henry, O'Meara, Matthew J, Scott, David A, Morris, John H, Russel, Daniel, Almo, Steven C, Osterman, Andrei L, Gerlt, John A, Jacobson, Matthew P, Shoichet, Brian K, Sali, Andrej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788505/
https://www.ncbi.nlm.nih.gov/pubmed/29377793
http://dx.doi.org/10.7554/eLife.31097

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