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Keeping Pace with the Red Queen: Identifying the Genetic Basis of Susceptibility to Infectious Disease
Genome-wide association studies are widely used to identify “disease genes” conferring resistance/susceptibility to infectious diseases. Using a combination of mathematical models and simulations, we demonstrate that genetic interactions between hosts and parasites [genotype-by-genotype (G × G) inte...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Genetics Society of America
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788537/ https://www.ncbi.nlm.nih.gov/pubmed/29223971 http://dx.doi.org/10.1534/genetics.117.300481 |