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Targeting the Golgi apparatus to overcome acquired resistance of non-small cell lung cancer cells to EGFR tyrosine kinase inhibitors

Epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (EGFR-TKIs) were demonstrated to provide survival benefit in patients with non-small cell lung cancer (NSCLC) harboring activating mutations of EGFR; however, emergence of acquired resistance to EGFR-TKIs has been shown to cause poor...

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Detalles Bibliográficos
Autores principales: Ohashi, Yoshimi, Okamura, Mutsumi, Katayama, Ryohei, Fang, Siyang, Tsutsui, Saki, Akatsuka, Akinobu, Shan, Mingde, Choi, Hyeong-Wook, Fujita, Naoya, Yoshimatsu, Kentaro, Shiina, Isamu, Yamori, Takao, Dan, Shingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788588/
https://www.ncbi.nlm.nih.gov/pubmed/29416720
http://dx.doi.org/10.18632/oncotarget.22895