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Hypericin targets osteoclast and prevents breast cancer-induced bone metastasis via NFATc1 signaling pathway
Bone is the most common target organ of metastasis of breast cancers. This produces considerable morbidity due to skeletal-related events, and severely reduces the quality of life. Increased osteoclast activity is implicated in breast cancer outgrowth in the bone microenvironment. Our previous obser...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788605/ https://www.ncbi.nlm.nih.gov/pubmed/29416737 http://dx.doi.org/10.18632/oncotarget.22930 |