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Experimental evidence of good efficacy and reduced toxicity with peptide-doxorubicin to treat gastric cancer
BACKGROUND: To compare the efficacy and toxicity of peptide-doxorubicin (PDOX) and doxorubicin (DOX) on nude mice models of human gastric cancer. RESULTS: Both PDOX and DOX could significantly inhibit tumor growth compared with Control (P < 0.05) in both subcutaneous and orthotopic models. Animal...
Autores principales: | Zhang, Jue, Yuan, Jing-Ping, Wang, Qun, Shao, Li-Hua, Liu, Shao-Ping, Firestone, Raymond A., Hong, Ya-Ping, Li, Ji-Guo, Xin, Yan-Chao, Li, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788612/ https://www.ncbi.nlm.nih.gov/pubmed/29416744 http://dx.doi.org/10.18632/oncotarget.23319 |
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