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Co-targeting of Tiam1/Rac1 and Notch ameliorates chemoresistance against doxorubicin in a biomimetic 3D lymphoma model

Lymphoma is a heterogeneous disease with a highly variable clinical course and prognosis. Improving the prognosis for patients with relapsed and treatment-resistant lymphoma remains challenging. Current in vitro drug testing models based on 2D cell culture lack natural tissue-like structural organiz...

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Detalles Bibliográficos
Autores principales:	Ikram, Muhammad, Lim, Yeseon, Baek, Sun-Yong, Jin, Songwan, Jeong, Young Hun, Kwak, Jong-Young, Yoon, Sik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788621/ https://www.ncbi.nlm.nih.gov/pubmed/29416753 http://dx.doi.org/10.18632/oncotarget.23156

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