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Nomogram predicting pulmonary metastasis of hepatocellular carcinoma after liver transplantation

A novel prognostic nomogram predicting post-transplant pulmonary metastasis was established with a primary cohort of 308 HCC patients who received liver transplantation between 2007 and 2011 at Ren Ji Hospital. The C-indexes for predicting pulmonary metastasis was 0.85. The calibration curves fitted...

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Autores principales: Huang, Li-Feng, Wan, Ping, Xu, Dong-Wei, Jeong, Seogsong, Feng, Ming-Xuan, Zhang, Jian-Jun, Xia, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788650/
https://www.ncbi.nlm.nih.gov/pubmed/29416782
http://dx.doi.org/10.18632/oncotarget.23418
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author Huang, Li-Feng
Wan, Ping
Xu, Dong-Wei
Jeong, Seogsong
Feng, Ming-Xuan
Zhang, Jian-Jun
Xia, Qiang
author_facet Huang, Li-Feng
Wan, Ping
Xu, Dong-Wei
Jeong, Seogsong
Feng, Ming-Xuan
Zhang, Jian-Jun
Xia, Qiang
author_sort Huang, Li-Feng
collection PubMed
description A novel prognostic nomogram predicting post-transplant pulmonary metastasis was established with a primary cohort of 308 HCC patients who received liver transplantation between 2007 and 2011 at Ren Ji Hospital. The C-indexes for predicting pulmonary metastasis was 0.85. The calibration curves fitted well between the predicted and actual outcomes. The decision curve analysis indicated that our nomogram was the optimal decision-making strategy for PM prediction compared to Milan, University of California San Franscisco, and up-to-seven criteria. These results were further validated by data from 103 patients who underwent liver transplantation between 2011 and 2012 at the same institution. In conclusion, our nomogram could be used as an effective tool to predict PM after liver transplantation.
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spelling pubmed-57886502018-02-07 Nomogram predicting pulmonary metastasis of hepatocellular carcinoma after liver transplantation Huang, Li-Feng Wan, Ping Xu, Dong-Wei Jeong, Seogsong Feng, Ming-Xuan Zhang, Jian-Jun Xia, Qiang Oncotarget Research Paper A novel prognostic nomogram predicting post-transplant pulmonary metastasis was established with a primary cohort of 308 HCC patients who received liver transplantation between 2007 and 2011 at Ren Ji Hospital. The C-indexes for predicting pulmonary metastasis was 0.85. The calibration curves fitted well between the predicted and actual outcomes. The decision curve analysis indicated that our nomogram was the optimal decision-making strategy for PM prediction compared to Milan, University of California San Franscisco, and up-to-seven criteria. These results were further validated by data from 103 patients who underwent liver transplantation between 2011 and 2012 at the same institution. In conclusion, our nomogram could be used as an effective tool to predict PM after liver transplantation. Impact Journals LLC 2017-12-19 /pmc/articles/PMC5788650/ /pubmed/29416782 http://dx.doi.org/10.18632/oncotarget.23418 Text en Copyright: © 2018 Huang et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (http://creativecommons.org/licenses/by/3.0/) (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Paper
Huang, Li-Feng
Wan, Ping
Xu, Dong-Wei
Jeong, Seogsong
Feng, Ming-Xuan
Zhang, Jian-Jun
Xia, Qiang
Nomogram predicting pulmonary metastasis of hepatocellular carcinoma after liver transplantation
title Nomogram predicting pulmonary metastasis of hepatocellular carcinoma after liver transplantation
title_full Nomogram predicting pulmonary metastasis of hepatocellular carcinoma after liver transplantation
title_fullStr Nomogram predicting pulmonary metastasis of hepatocellular carcinoma after liver transplantation
title_full_unstemmed Nomogram predicting pulmonary metastasis of hepatocellular carcinoma after liver transplantation
title_short Nomogram predicting pulmonary metastasis of hepatocellular carcinoma after liver transplantation
title_sort nomogram predicting pulmonary metastasis of hepatocellular carcinoma after liver transplantation
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788650/
https://www.ncbi.nlm.nih.gov/pubmed/29416782
http://dx.doi.org/10.18632/oncotarget.23418
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