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Identification of differentially expressed genes in human breast cancer cells induced by 4-hydroxyltamoxifen and elucidation of their pathophysiological relevance and mechanisms

While tamoxifen (TAM) is used for treating estrogen receptor (ER)a-positive breast cancer patients, its anti-breast cancer mechanisms are not completely elucidated. This study aimed to examine effects of 4-hydroxyltamoxifen (4-OH-TAM) on ER-positive (ER(+)) breast cancer MCF-7 cell growth and gene e...

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Detalles Bibliográficos
Autores principales: Fang, Qi, Yao, Shuang, Luo, Guanghua, Zhang, Xiaoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788654/
https://www.ncbi.nlm.nih.gov/pubmed/29416786
http://dx.doi.org/10.18632/oncotarget.23504

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