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MELK is a novel therapeutic target in high-risk neuroblastoma

Maternal embryonic leucine zipper kinase (MELK) is known to modulate intracellular signaling and control cellular processes. However, the role of MELK in oncogenesis is not well defined. In this study, using two microarray datasets of neuroblastoma (NB) patients, we identified that MELK expression i...

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Detalles Bibliográficos
Autores principales: Guan, Shan, Lu, Jiaxiong, Zhao, Yanling, Yu, Yang, Li, Hui, Chen, Zhenghu, Shi, Zhongcheng, Liang, Haoqian, Wang, Mopei, Guo, Kevin, Chen, Xiangmei, Sun, Wenjing, Bieerkehazhi, Shayahati, Xu, Xin, Sun, Surong, Agarwal, Saurabh, Yang, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788662/
https://www.ncbi.nlm.nih.gov/pubmed/29416794
http://dx.doi.org/10.18632/oncotarget.23515