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T Cells Engaging the Conserved MHC Class Ib Molecule Qa-1(b) with TAP-Independent Peptides Are Semi-Invariant Lymphocytes

The HLA-E homolog in the mouse (Qa-1(b)) is a conserved MHC class Ib molecule presenting monomorphic peptides to germline-encoded natural killer receptor CD94/NKG2A. Previously, we demonstrated the replacement of this canonical peptide by a diverse peptidome upon deficiency of the TAP peptide transp...

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Detalles Bibliográficos
Autores principales: Doorduijn, Elien M., Sluijter, Marjolein, Querido, Bianca J., Seidel, Ursula J. E., Oliveira, Claudia C., van der Burg, Sjoerd H., van Hall, Thorbald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788890/
https://www.ncbi.nlm.nih.gov/pubmed/29422902
http://dx.doi.org/10.3389/fimmu.2018.00060