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Plasma Prekallikrein: Its Role in Hereditary Angioedema and Health and Disease
Plasma prekallikrein (PK) has a critical role in acute attacks of hereditary angioedema (HAE). Unlike C1 inhibitor, its levels fall during HAE attacks with resultant cleaved high-molecular-weight kininogen. Cleavage of high-molecular-weight kininogen liberates bradykinin, the major biologic peptide...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788901/ https://www.ncbi.nlm.nih.gov/pubmed/29423395 http://dx.doi.org/10.3389/fmed.2018.00003 |