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Prolonged-release oxycodone/naloxone reduces opioid-induced constipation and improves quality of life in laxative-refractory patients: results of an observational study

BACKGROUND: Opioids are an effective treatment for moderate-to-severe pain. However, they are associated with a number of gastrointestinal side effects, most commonly constipation. Laxatives do not target the underlying mechanism of opioid-induced constipation (OIC), so many patients do not have the...

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Detalles Bibliográficos
Autores principales: Bantel, Carsten, Tripathi, Shiva S, Molony, David, Heffernan, Tony, Oomman, Susmita, Mehta, Vivek, Dickerson, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788929/
https://www.ncbi.nlm.nih.gov/pubmed/29416370
http://dx.doi.org/10.2147/CEG.S143913

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