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Identifying Potential Plasmodium vivax Sporozoite Stage Vaccine Candidates: An Analysis of Genetic Diversity and Natural Selection
Parasite antigen genetic diversity represents a great obstacle when designing a vaccine against malaria caused by Plasmodium vivax. Selecting vaccine candidate antigens has been focused on those fulfilling a role in invasion and which are conserved, thus avoiding specific-allele immune responses. Mo...
Autores principales: | Garzón-Ospina, Diego, Buitrago, Sindy P., Ramos, Andrea E., Patarroyo, Manuel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788960/ https://www.ncbi.nlm.nih.gov/pubmed/29422913 http://dx.doi.org/10.3389/fgene.2018.00010 |
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