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Reconstruction of cysteine biosynthesis using engineered cysteine-free enzymes

Amino acid biosynthesis pathways observed in nature typically require enzymes that are made with the amino acids they produce. For example, Escherichia coli produces cysteine from serine via two enzymes that contain cysteine: serine acetyltransferase (CysE) and O-acetylserine sulfhydrylase (CysK/Cys...

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Detalles Bibliográficos
Autores principales: Fujishima, Kosuke, Wang, Kendrick M., Palmer, Jesse A., Abe, Nozomi, Nakahigashi, Kenji, Endy, Drew, Rothschild, Lynn J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788988/
https://www.ncbi.nlm.nih.gov/pubmed/29379050
http://dx.doi.org/10.1038/s41598-018-19920-y

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