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Antibody targeting of phosphatidylserine for the detection and immunotherapy of cancer
Phosphatidylserine (PS) is a negatively charged phospholipid in all eukaryotic cells that is actively sequestered to the inner leaflet of the cell membrane. Exposure of PS on apoptotic cells is a normal physiological process that triggers their rapid removal by phagocytic engulfment under noninflamm...
Autores principales: | Belzile, Olivier, Huang, Xianming, Gong, Jian, Carlson, Jay, Schroit, Alan J, Brekken, Rolf A, Freimark, Bruce D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788995/ https://www.ncbi.nlm.nih.gov/pubmed/29417044 http://dx.doi.org/10.2147/ITT.S134834 |
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